The New Choice of Tacrolimus in the Treatment of Refractory Ulcerative Colitis
MOJ bioequivalence & bioavailability（2015）
Abstract
Recent studies have found that a new immuno-suppressant of tacrolimus (Tacrolimus, FK506) has the effect of inducing remission and maintaining therapy in the treatment of Ulcerative Colitis.Its mechanism may be correlated with the inhibition of T cells and related cytokines.This mini review will summarize the anti-inflammatory mechanisms of tacrolimus and provide a brief overview of several up to date clinical studies on tacrolimus in UC treatment.
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