Cytotoxic steroidal saponins from the rhizomes of Paris fargesii var. Petiolata

Bioorganic Chemistry(2022)

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Abstract
•The isolation and identification of the chemical compounds from Paris fargesii var. petiolata were studied.•Eleven steroidal saponins were characterized from the plant, including five new steroid saponins (1–5) and six known analogues (6–11).•Compound 1 displayed certain anti-proliferative properties for U87, HepG2 and SGC-7901 cells.
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Key words
Paris fargesii var. petiolata,Isospirostanol-type saponins,Furostanol-type saponins,Cholestanol-type saponins,Cytotoxic,Cell cycle arrest
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