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基质金属蛋白酶-9及其抑制剂TIMP-1与支气管哮喘

JOURNAL OF CHINESE PHYSICIAN(2007)

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Abstract
基质金属蛋白酶家族(MMPS)是一组在结构上具有极大同源性能降解细胞外基质(ECM)蛋白的内肽酶的总称.家族成员目前有25个,分5大类.MMP-9为明胶酶B,与支气管哮喘的关系最密切.复习有关文献,就MMP-9及其抑制物与哮喘的关系综述如下.
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