Influence Of Nanochannel Inlet Structure Upon Dna Capture Ratio

DNA molecule will be stretched to its near full contour length inside a nanochannel when the channel diameter is less than the DNA persistence length.1–3 It provides the possibility of real time lab-free-analysis of analysis, such as screening of sequence variations of DNA molecules.3 The key process for this nanochannel-based analysis is to drive DNA molecule electrophoretically through the nanochannel and read out the information of the DNA chain while it is passing the channel.2, 3