Pre-Clinical Study Of The Drug Izatizon

Introduction. In order to expand the range of action of the drug solution was obtained metysazon form- izatizon,the use of which demonstrates the need for further investigation for use in the clinic.Materials and methods. Experimental studies of the Potential drug izatizon were conducted by spectral analysis and the method of dynamic light scattering instrument at SPECORD UA VIS, 90plus S/n Brookhaven Instruments Corporation.Results. It was determined that the drug has the Izatizon peaks 244,0; 274,0; 360,0. The best concentration of drug research is 1 ml/1. The size of particles in water 775,0 nm., And DMSO - 148,0 nm. The value of the zeta potential of the particles of the drug izatizon corresponds to -4,1. The product has two peaks in the UV region of the spectrum, indicating a complex structure and a peak in the visible range - the presence of yellow color. The size and zeta potential drug particles play an important role in the body led them in vivo. The best concentration for research on a spectrophotometer is 1 ml/1.