Guidelines For Diagnosis, Staging And Treatment Of Metastatic Colorectal Cancer By Grupo Espanol Multidisciplinar En Cancer Digestivo (Gemcad) G Aguilar , S Albiol , J Alcaide , Martina Alonso , Vicente Alonso , Montserrat Andreu , Jorge Aparicio , Fernando Arias De La Vega , A Arrivi , Juan Ramon Ayuso , U Bohn , R Bouzas , J M Cano , C Castanon , Antoni Castells , Paula Cerda , Laura Cerezo , Carles Conill , Miriam Cuatrecasas , Ma Nieves Del Pozo , J Delgado , Jose M Enriqueznavascues , Pilar Escudero , Eloy Espin , Rafael Estevan L , E Falco , Jose Farre , Jaime Feliu , Carlos Fernandezmartos , A Ferrer , Rosa Gallego , Elisa Galvez , Xabier Garcia De Albeniz , Damian Garcia Olmo , Rocio Garciacarbonero , M Dorronsoro , C Martin , Santiago G Moreno , Ana Maria Hernandez , Amparo Iraola , E Jimenez , Manuel Cecilio Jimenez , Ismael Jurado , Ruben Leno , Ana Leon , Elena Manzano Martin , M Martin , Joan Maurel , J Mendez , Ramiro Mendez , Pablo Palma , Fernando Pardo , Fernando Pereira , Javier Perezaltozano , Elisabet Perez , Javier Rodriguez , Ana Ruizcasado , Luis Sabater , Luis Sarria , Angel Segura , Isabel Sevilla , M Tobena , Esperanza Torres , A Viudez , Montserrat Zanui , M Zorrilla COLORECTAL CANCER（2015）
Abstract
Advances in the care of patients with metastatic colorectal cancer arise from well-designed clinical trials. In the present document we address specific challenges in the design of clinical trials for metastatic colorectal cancer regarding staging and standard of care according to prognosis, as well as some relevant methodological issues.
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Key words
classification, colorectal cancer, prognosis, treatment, trial design
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