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Immunohistochemical Study of the Expression of HLA-DR Antigen and Lymphocyte Infiltration in Human Esophageal Carcinoma

Kanji Tanaka,Mika Morita,Takayuki Motohiro,Hideharu Yamanaka,Yasushi Nakane,Koshirou Hioki

RECENT ADVANCES IN DISEASES OF THE ESOPHAGUS（1993）

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Abstract
The major histocompatibility complex (MHC) class II antigen HLA-DR is known to be present on many types of immunocompetent cells, involved in a variety of immune functions, and can be found in various kinds of cancer cells of the gastrointestinal tract. It is also reported that HLA-DR is associated with tumor invasion, tumor metastasis, and patient survival [1].
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Key words
Major Histocompatibility Complex, Esophageal Squamous Cell Carcinoma, Esophageal Carcinoma, Lymphocyte Infiltration, Esophageal Squamous Cell Cancer
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