Effect of adenotonsillectomy on nocturnal enuresis in children with OSA

Background: Pediatric obstructive sleep apnea (OSA) is the most severe form of SDB. The most important risk factors for the development of pediatric SDB include adenotonsillar hypertrophy. On the other hand, nocturnal enuresis is common symptom that is associated with (OSA), through influencing the nocturnal secretion of antidiuretic hormone (ADH).Objective: We aimed to study the relation between polysomnography data of children with OSA due to adenotonsillar hypertrophy and levels of ADH, total and night urine volume.Subject and method: The study included 23 Consecutive non obese children with age above 5 years old, complaining of nocturnal enuresis, hypertrophied adenoids and tonsils. A polysomnographic evaluation was done together with serum level of ADH, total and nocturnal urine volume were measured pre and 3 months post adenotonsillectomy.Results: There was a significant negative correlation between ADH and different polysomnographic data including respiratory events (apnea index, total hypopneas, hypopnea index and RDI), oxygen saturation data and the snoring index. There was also a significant negative correlation between night urine volume and desaturation index. comparison between the data means before and after adenoidectomy were done using the paired t-test; showed a significant improvement of all the polysomnographic data values, and a significant improvement in serum level of ADH, besides the significant decrease in both the 24 h urine volume and the night urine volume being.Conclusion: Children with OSA and nocturnal enuresis, should be considered for early adeno-tonsillectomy or other treatments to approve normal release of ADH, and subsequent improvement of nocturnal enuresis. (C) 2013 Production and hosting by Elsevier B.V.