Therapeutic Potential Of Interleukin-27 Against Cancers In Preclinical Mouse Models
ONCOIMMUNOLOGY(2015)
摘要
Since we first reported the antitumor efficacy of IL-27 in 2004, accumulating evidence obtained by several groups using a variety of preclinical mouse models indicates that IL-27 possesses potent antitumor activity against various types of tumors through multiple mechanisms depending on the characteristics of individual tumors without apparent adverse effects.
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关键词
antitumor,IL-27,poly(I:C),TLR3,TRAIL
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