In vivo Imaging of Oral Cancer using a Multimodal Probe combining Fluorescence Lifetime, Photoacoustic and Ultrasound Techniques

Conrad Merkle,Laura Marcu, Hussain Fatakdawalaa,Yang Sun,Feifei Zhou,D Gregory Farwell

Optics in the Life Sciences (2013), paper BM2A.3（2013）

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Abstract

We report a multimodal system combining fluorescence lifetime imaging (FLIM), photoacoustic imaging (PAI) and ultrasound backscatter microscopy (UBM). The system provides complimentary diagnostic features allowing for enhanced in-vivo detection of oral carcinoma.

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Key words

oral cancer,vivo imaging,photoacoustic,fluorescence lifetime,multimodal probe

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