A Safety and Efficacy Study of Medium-Dose Etoposide, Cyclophosphamide and Total Body Irradiation Conditioning Before Allogeneic Stem Cell Transplantation for Acute Lymphoblastic Leukemia.

Akio Shigematsu,Yukiyasu Ozawa,Makoto Onizuka,Shin Fujisawa,Ritsuro Suzuki,Yoshiko Atsuta,Kazuo Hatanaka,Masayoshi Masuko,Toshiro Ito,Naoki Kobayashi,Jun Kato,Koichi Miyamura,Takahiro Fukuda,Yasuo Morishima,Masahiro Imamura

TRANSPLANTATION DIRECT（2015）

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摘要

Medium-dose etoposide + CY + TBI is an effective conditioning before allo-SCT for adult patients with ALL, enabling good disease control without an increase in nonrelapse mortality. A phase 3 trial comparing this regimen with the standard CY + TBI regimen for adult patients with ALL is warranted.

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