Cross validation of pooling/resampling GWAS using the WTCCC data
Molecular Biology and Genetic Engineering(2015)
摘要
Introduction In a recent manuscript we presented a new strategy for genome wide association studies (GWAS) that uses resampling and DNA pooling, and that we denominated pooling/bootstrap-based GWAS (prGWAS) [1]. This methodology is well suited to identify disease-associated genetic variants using limited and relatively small samples at a fraction of
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