PM197 Clinical Characteristics, Trends and Outcomes in Elderly Patients with Acute Coronary Syndromes Undergoing PCI

O ST E R A B ST R A C T S Objectives: In this study we evaluate the relationship between recent glycaemic control (measured as %HbA1c) and hospital outcomes in DM patients presenting with an ACS. Methods: Demographic and clinical data were evaluated using the CONCORDANCE registry, obtained from 23 Hospitals across Australia. The analysis included 351 patients with a final diagnosis of ACS, previous history of DM and HbA1c level measured during admission. Patient characteristics and hospital events were analysed using Chi-square tests. Patient outcomes were compared using Chi-squared tests, and adjusted odds ratios (OR) and corresponding 95% confidence intervals (CI) using multivariable logistic regression. Results: 114 (32.5%) patients had good glycaemic control (HbA1c 9%). Patients with HbA1c >9% were significantly more likely to be current smokers, indigenous, have non-English speaking background, present at younger age and have higher admission levels of blood glucose and total cholesterol. Patients with HbA1c >9% were significantly more likely to receive statins in hospital, compared to patients with HbA1c <7%. No significant association was found between %HbA1c and other measures of inhospital management (Table). In hospital deaths were infrequent in this cohort (n1⁄49) and, after adjusting for GRACE risk score, no difference in hospital mortality was found between patients with HbA1c 7% and patients with HbA1c <7% (OR 1.75, 95% CI 0.22-13.65).