Subchondral Bone Trabecular Integrity Predicts and Changes Concurrently with Radiographic and MRI Determined Knee Osteoarthritis Progression

*These authors contributed equally to this work: Department of Medicine, Biostatistics and Bioinformatics, and Duke Image Analysis Laboratory, Department of Radiology, Duke University, Durham, NC 27710; Pfizer Global Research and Development, Groton, CT, USA; Optasia Medical, Manchester, UK; Institute of Anatomy & Musculoskeletal Research, Paracelsus Medical University (PMU), Salzburg, Austria & Chondrometrics GmbH, Ainring, Germany; New England Baptist Hospital, Boston, MA and Institute of Bone and Joint Research, University of Sydney, Sydney, Australia; University of California at Davis Medical Center, Sacramento, CA; University of Arizona, Tuscon, AZ; Northwestern University, Chicago, IL.