PTPRK, an EGFR Phosphatase, Is Decreased in CeD Biopsies and Intestinal Organoids.

Merlin Nanayakkara, Claudia Bellomo, Francesca Furone, Mariantonia Maglio, Antonella Marano, Giuliana Lania, Monia Porpora, Martina Nicoletti, Salvatore Auricchio, Maria Vittoria Barone

Cells（2022）

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摘要

modulation of PTPRK levels can reduce or increase pEGFR, pERK and proliferation in CeD or CTR organoids, respectively. The CeD organoids can be a good model to study the mechanisms of the disease.

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关键词

EGFR,PTPRK,celiac disease,intestinal organoids

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