Natural Product Screening

HANDBOOK OF ANTICANCER PHARMACOKINETICS AND PHARMACODYNAMICS, 2ND EDITION(2014)

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摘要
Natural product screening marries the search for new medicines with the search for new molecules from natural sources. The rationale for natural products as a source for new hits from which to develop new drugs will be discussed, and a brief overview of screening methods and techniques including how these are modified for the screening of crude natural product extracts will be described. This chapter will also provide a summary of the importance of natural products to drug discovery and development, the results from screening assays developed, and the natural products isolated utilizing these screens.
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关键词
Screening,Natural products,Assay development,Phenotypic screen,Biochemical screen,Nuisance compounds
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