Autofluorescence Imaging Resolves Early Cancer Treatment Response In Vivo

Melissa C Skala, Carlos L Arteaga,Alec Lafontant,Donna Hicks,H C Manning,Rebecca S Cook,Alex J Walsh

Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013（2013）

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摘要

NADH and FAD auto-fluorescence intensity and lifetime imaging are used to monitor breast cancer metabolism. In vivo imaging of xenograft tumors revealed metabolic differences in responsive but not resistant tumors treated with trastuzumab at earlier time points than FDG-PET.

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autofluorescence imaging resolves,early cancer treatment response

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