An Evans Syndrome Case Expressing Anti-Jk<sup>a</sup> Autoantibody under Condition of Primary IgA Immunodeficiency

Takeshi Sugimoto, Ayumi Tani, Ikuyo Hayakawa,Makoto Hashimoto, Tomoko Yanai, Ikuko Kubokawa,Takeshi Mori,Takeshi Kato,Satoshi Hirase,Nobuyuki Yamamoto,Hironobu Minami,Akira Hayakawa

International Journal of Clinical Medicine(2015)

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摘要
Autoimmune haemolytic anaemia is a haemolytic disease resulting from an autoimmune reaction to the surface of red blood cells. A part of autoantibody is known to react with the blood type antigen. This is the case of a 14 years old female with Evans syndrome in which autoimmune haemolysis may cause from anti-Jka autoantibody reaction. As this case is complicated with primary IgA immunodeficiency syndrome, anti-Jka autoantibody may occur under the condition of primary immunodeficiency status, in which autoantibody production is accelerated. Considering the co-occurrence of autoimmune haemolytic anaemia and primary IgA immunodeficiency syndrome, analysis focusing on specificity for red blood cells antigens will be required in IgA immunodefi-ciency syndrome patients.
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autoantibody
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