Identification of new manioc allergens and successful oral immunotherapy in a Brazilian allergic patient

Background Brazil is a tropical country that shows a great biodiversity and is a rich source of new allergens especially from foods. Exotic tropical fruits and plants are highly consumed in the country and due to globalization these products are being exported worldwide. We have recently described the first manioc allergen Man e 5 that cross-reacts with Hev b 5 from latex. There are more than 70 products made up manioc starch such as drugs, soaps and fabrics and manioc allergic patients present from mild to severe reactions.