1245PA PHASE 3 RANDOMISED TRIAL OF ADDING NITROGLYCERIN TO FIRST LINE CHEMOTHERAPY FOR ADVANCED NON-SMALL CELL LUNG CANCER: THE AUSTRALASIAN LUNG CANCER TRIALS GROUP NITRO TRIAL.

Davidson A,Veillard A S,Tognela A, Chan M M K,Briscoe K,Hughes B,Boyer M,Begbie S, Muljadi N,Coskinas X,Chinchen S,Millward M,Pavlakis N,Stockler M R

Annals of oncology : official journal of the European Society for Medical Oncology（2014）

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摘要

Aim: We sought to determine if the substantial benefits seen in a Japanese phase 2 trial of adding transdermal nitroglycerin to cisplatin and vinorelbine as first line chemotherapy for advanced non-small cell lung cancer (NSCLC) could be corroborated in a multicentre phase 3 trial with widely used platinum-based doublets.

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Tumor Microenvironment

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