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A New Animal Model for Polygonum Multiflorum Thunb-Induced Liver Injury in Rats and Its Potential Mechanisms

Xing Fan,Jiabo Wang,Lihua Xie,Yansheng Dong,Gang Han,Dan Hu,Yue Liu,Benli Yuan,Hemei Wang,Chunqi Wu, Xiaohe Xiao,Rigao Ding,Quanjun Wang

Toxicology research（2015）

Cited 9|Views38
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Abstract
The model is established successfully with the activation of LPS. Its pathogenesis is associated with the expression of mTLR4 in rats' liver. MicroRNA-122 is certificated to be an ideal potential serum biomarker for this model.
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