Two Common Drugs Promote Remyelination in Demyelinating Disease of Mice
NEJM Journal Watch(2015)
摘要
In multiple sclerosis (MS) and other demyelinating diseases, autoimmune attacks lead to demyelination. Approved therapies for MS target this immune attack and prevent further demyelination. An alternative approach to treating demyelination would be to encourage remyelination. Oligodendrocytes in the central nervous system have the ability to promote remyelination; however, in humans (and other mammals), remyelination …
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