Cooccurrence of Pulmonary Carcinoma and Gastric Carcinoma in a Dog

A 15-year-old, female mongrel dog was presented due to loss of general physical conditions with anorexia. From the physical examination, thoracic radiographs and ultrasonography, the dog was diagnosed as primary lung tumor and treated with a combination protocol of vincristine, cyclophosphamide and prednisolone. After 6 weeks of treatment, thoracic radiography showed a remission of the size of the pulmonary mass, while the general conditions did not recover. Lobectomy was then perfomed, and a surgical biopsied sample of the pulmonary mass was examined and diagnosed histopathologically as bronchiolar-alveolar carcinoma. There was no gross and histopathological evidence of local metastasis of the pulmonary carcinoma, but gastric scirrhus carcinoma had metastasized to many organs and tissues systematically. Massive necrosis of tumor tissue, which seemed to be attributable to the chemotherapeutic effect, occurred in the pulmonary carcinoma, but not in the gastric carcinoma.