Comparative Analyses of Anti-hypertensive Effects of Commercial Collagen Peptides in Spontaneously Hypertensive Rats

In this study, we investigated the anti-hypertensive effects of two enzymatic hydrolysates of chicken and pig collagens in spontaneously hypertensive rats (SHR). SHR were divided into three groups and administrated collagen peptides at 3 g/kg body weight, or water for 14 weeks. In the chicken collagen peptides group, systolic blood pressure was significantly reduced when compared with the control group, and diastolic blood pressure was also reduced when compared to the pig collagen group. Microscopic analysis revealed that inflammation in liver and heart was mildly ameliorated in the chicken collagen peptides group.