Loss Of Vancomycin-Resistant Enterococcus Fecal Dominance In An Organ Transplant Patient With Clostridium Difficile Colitis After Fecal Microbiota Transplant

We report the use of fecal microbiota transplantation in a single heart-kidney transplant recipient with recurrent Clostridium difficile, vancomycin-resistant Enterococcus (VRE) fecal dominance, and recurrent VRE infections. Fecal microbiota transplantation resulted in the reconstruction of a diverse microbiota with (1) reduced relative abundance of C difficile and VRE and (2) positive clinical outcome.