Immunogenicity and safety of a second administration of 13-valent pneumococcal conjugate vaccine 5 years after initial vaccination in adults 50 years and older

Vaccine(2016)

Cited 25|Views29
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Abstract
•Adults ≥50 years, were revaccinated with PCV13 five years after initial vaccination.•Immune responses significantly increased from before to 1 month after revaccination.•Immune responses were maintained or enhanced for most vaccine serotypes by revaccination.•The safety profile after PCV13 revaccination was acceptable.
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Key words
ACIP,AE,CAPiTA,CI,CRM197,GMC,GMFR,GMT,IgG,IPD,OPA,PCV13,PCV,PPSV23,SAEs,TIV
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