5-androstene 3β,17α diol induces autophagic cell death of human breast cancer cells and enhances radiation cytotoxicity

Roger M Loria,Martin R Graf,Jia Wentao, Tiffany Powell

journal of Cancer Therapeutics and Research（2012）

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摘要

Abstract Herein, we demonstrate that the steroid, 5-androstene 3β,17α diol (17α-AED) induced cell death in human breast cancer cells MCF-7, MDA-MB231, T47D and TTU-1 at clinically relevant levels. 17α-AED

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breast cancer,autophagy

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