瑞舒伐他汀对急性脑梗死患者血清抵抗素 TNF-α的影响
The Medical Forum(2014)
Abstract
目的:探讨急性脑梗死患者应用瑞舒伐他汀治疗后对血脂、血清抵抗素和肿瘤坏死因子α(TNF-α)水平的影响。方法选择急性脑梗死患者103例,随机分为对照组50例和观察组53例,2组均给予常规治疗,观察组加用瑞舒伐他汀治疗。2组患者均治疗2周,比较2组治疗前后血脂、血清抵抗素、TNF-α水平的变化。结果2组患者治疗后TC、TG、LDL-C、血清抵抗素、TNF-α水平均较治疗前明显下降,观察组较对照组下降更显著,差异均有统计学意义(P<0.05);2组治疗后H DL-C水平均升高,观察组较对照组升高更显著,差异有统计学意义(P<0.05)。结论瑞舒伐他汀能降低脑梗死患者的血脂、血清抵抗素和TNF-α水平从而防治脑梗死。
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