Pattern of care and effectiveness of treatment for glioblastoma patients in the real world: Results from a prospective population-based registry. Could survival differ in a high-volume center?

Alba A Brandes,Enrico Franceschi,Mario Ermani,Alicia Tosoni,Fiorenzo Albani,Roberta Depenni,Marina Faedi,Anna Pisanello,Girolamo Crisi,Benedetta Urbini,Claudio Dazzi,Luigi Cavanna,Claudia Mucciarini,Giuseppe Pasini,Stefania Bartolini,Gianluca Marucci,Luca Morandi,Elena Zunarelli,Serenella Cerasoli,Giorgio Gardini,Giovanni Lanza,Enrico Maria Silini,Silvio Cavuto,Agostino Baruzzi,A Baruzzi,F Albani,F Calbucci,R D'Alessandro,R Michelucci,A Brandes,V Eusebi,S Ceruti,E Fainardi,R Tamarozzi,E Emiliani,M Cavallo,E Franceschi,A Tosoni,M Cavallo,F Fiorica,A Valentini,R Depenni,C Mucciarini,G Crisi,E Sasso,C Biasini,L Cavanna,D Guidetti,N Marcello,A Pisanello,A M Cremonini,G Guiducci,S de Pasqua,S Testoni,R Agati,G Ambrosetto,A Bacci,E Baldin,A Baldrati,E Barbieri,S Bartolini,E Bellavista,F Bisulli,E Bonora,F Bunkheila,V Carelli,M Crisci, P Dall'Occa,D de Biase,S Ferro,C Franceschi,G Frezza, V Grasso,M Leonardi,G Marucci,V Mazzocchi,L Morandi,B Mostacci,G Palandri,E Pasini,M Pastore Trossello,A Pession,M Ragazzi,P Riguzzi,R Rinaldi,S Rizzi, G Romeo,F Spagnolli,P Tinuper, C Trocino,S Cerasoli,M Dall'Agata,M Faedi,M Frattarelli,G Gentili, A Giovannini,P Iorio,U Pasquini, G Galletti,C Guidi,W Neri, A Patuelli,S Strumia,M Casmiro,A Gamboni,F Rasi,G Cruciani,P Cenni,C Dazzi,Ar Guidi,F Zumaglini,A Amadori,G Pasini,M Pasquinelli,E Pasquini,A Polselli,A Ravasio, B Viti,M Sintini,A Ariatti,F Bertolini,G Bigliardi,P Carpeggiani,F Cavalleri,S Meletti,P Nichelli,E Pettorelli,G Pinna,E Zunarelli,F Artioli,I Bernardini, M Costa,G Greco,R Guerzoni,C Stucchi,C Iaccarino,R Rizzi,G Zuccoli,P Api,F Cartei,E Fallica,E Granieri,F Latini,G Lelli,C Monetti, V Ramponi,A Saletti,R Schivalocchi,S Seraceni,M R Tola,B Urbini,C Giorgi,E Montanari,D Cerasti,P Crafa,I Dascola,I Florindo,S Mazza,F Servadei,Em Silini, P Torelli,P Immovilli,N Morelli,C Vanzo

Neuro-oncology practice（2014）

Cited 30|Views83

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Abstract

The median OS following standard temozolomide treatment concurrent with and adjuvant to radiotherapy given to (72.8% of) patients aged ≤70 years is consistent with findings reported from randomized phase III trials. The volume and expertise of the treatment center should be further investigated as a prognostic factor.

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Key words

center volume,glioblastoma,radiotherapy,surgery,temozolomide

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