A CASE OF MALIGNANT LYMPHOMA ARISING IN THE BREAST

A case of primary malignant lymphoma arising in the breast is reported. A 35-year-old woman visited a near by hospital because a palpable and painless mass in the left breast, which was noticed in May 1991, showed an increasing tendency. Excision of the tumor was carried out. Histopathologically it was found a malignant lymphoma and the patient was transferred to the hospital. On admission no tumor nor superficial lymph node was palpable in the bilateral breasts. As a result of general Gallium scintigraphy and other methods, no other tumor nor swelled lymph node was revealed. Histophatologically the lymphoma was of B lymphocyte origin, and was diffuse type, medium-sized cell type by LSG classification. From the above, the tumor was diagnosed as primary malignant lymphoma of the breast in Stage IA by Ann-Arbor classification. On June 13 1991 left simple mastectomy with left axillary lymph node dissection was performed. As postoperative chemotherapy, epirubicin hydrochloride 10 mg on the first postoperative day and cyclophosphamide 100 mg on the 8th day were intravenously administered. Oral cyclophosphamide 100 mg was strated since the 6th day. Postoperative course was uneventful and the patient was discharged from the hospital on June 27 1991. There has been no signs of recurrence and metastasis up to now.