EFFECTIVE AND REGIOSELECTIVE 5-IODINATION OF PYRIMIDINE BASES AND CORRESPONDING NUCLEOSIDES BY AN INEXPENSIVE IODINE-SODIUM NITRITE REAGENT

Coden Hleeai,Leena M Patil,Datta E Ponde,Shriniwas D Samant, N M Parekh

HETEROCYCLIC LETTERS（2014）

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摘要

A new eco-friendly method for the regioselective5-iodination of pyrimidine bases and the corresponding nucleosides at room temperature with iodine and sodium nitrite is developed. The method is simple and gives high yield in less reaction time under mild reaction conditions.

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关键词

Iodination, Pyrimidine bases, Nucleosides, Iodine and Sodium nitrite

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