Strongly enhanced guanine electrooxidation caused by temperature induced volume-phase- and conformational transitions in DNA/PNIPA composites

Nanostructured DNA/poly(N-isopropylacrylamide) PNIPA composites were synthesized. DNA was noncovalently entrapped. A strongly enhanced electrooxidation current of DNA guanine was obtained due to cooperation of two temperature switchable effects: the volume phase transition of composites and conformational transition of DNA structure.