Low energy electron generator design and depth dose prediction for micro-superficies tumors treatment purposes

PHYSICA SCRIPTA(2014)

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摘要
We investigate deposited energy and linear energy transfer (LET) of low energy ejection electrons in air and water layers of a generator design via a plasma source. A structured model of a concave cold cathode electron generator was designed and simulated by using Monte Carlo n-particle version X 2.7.0 (MCNPX) code. A negative dc high voltage was applied to a concave cathode up to -12 kV to determine electron energy activity. Results determined that the geometric dimensions of field size toward the anode increased in relation to the angle of the conic beam, widening the accumulated bulks. The increased field size increased the anode current, which also resulted in an increase of electron energy, a reduction in LET, a stretched build-up area and a dose curve that shifted to a higher depth. The biological effect of low energy electron radiation can be increased with an increase of LET; as the depth dose decreased, the electron energy increased at the same time. The study of electron irradiation as a conic beam from an electron generator may provide an accurate investigation of the indirect effect of low energy electrons on bystander cells.
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关键词
plasma source,electron generator,low energy electron,depth dose,MCNPX code
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