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Mass spectrometry signal enhancement by reductive amination

Mengchieh Liu, Yireng Lin,Meifang Huang,Decheng Tsai,Shihshin Liang

International Journal of Mass Spectrometry（2015）

Cited 6|Views4
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Abstract
•We enhance signal intensities of four organosulfur compounds (OSCs) in MS.•The factor of signal enhancement is a formaldehyde modification.•We demonstrate infusion, SIM and MRM to compare different compounds.•Signal intensities of four OSCs increase from 146.4 to 2494.8 folds by MRM.
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Key words
Reductive amination,Signal enhancement,Mass spectrometry,Multiple reaction monitoring (MRM)
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