Silver-Prompted Carbonitration Of Acrylamides For The Synthesis Of Nitrating Oxindoles

Xiao-Hong Wei,Quan-Xiang Wu,Shang-Dong Yang

Synlett（2015）

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摘要

A silver-prompted carbonitration of alkenes involving concomitant direct C-H functionalization and C-N bond formation to synthesize nitrating oxindoles has been developed. The CR TH2 receptor antagonist skeleton can be obtained from one of the products with further modification.

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关键词

silver,N-methyl-N-arylacrylamide,carbonitration,nitrating oxindoles

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