Inhibition Of Buprenorphine Metabolism By Proton Pump Inhibitors: Enigmatic Time-Dependent Effect Of Esomeprazole

The FASEB Journal（2014）

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摘要

While several studies have investigated the effect of proton pump inhibitors (PPI) on the activities of specific cytochrome P450s (CYP450), most studies used model substrates. Here we investigate t...

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Drug Efflux Pumps

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