Determinants of Disease Outcome in Patients with Drainage of Aortic Root Abscess Caused by Infective Endocarditis

The aim of this study was to investigate the factors that determine disease outcome in patients with drainage of aortic root abscess caused by infective endocarditis. Data from 27 patients who were treated for aortic root abscess due to infective endocarditis were analyzed. Nineteen patients survived for more than 3 years after discharge, seven patients died within 1 month after the surgery, and one patient died during the surgery. Based on survival or terminal outcome, patients were divided into two groups. There was no significant difference between surviving or dead patients in terms of age or gender. Other factors, such as disease course, surgery, cardiac function, pathology, pathogenic microorganisms, complications, and nosocomial infections were significantly different between patient groups and appear to be associated with disease outcome. Patients' deaths can be reduced through targeted clinical therapy.