Management of the Case of a Young Female Patient with Multiple Malignancies and Germline R24P CDKN2A Gene Mutation

The case of a young female patient with metachronous primary melanomas, advanced breast and pancreatic cancers is reported.The 5 different tumors diagnosed within six years, were managed with curative intent.Genetic analysis revealed the mutation of the R24P CDKN2A gene in a heterozygote form in both the patient and her father.Careful tertiary prevention during the follow-up of the patient is needed.