B-Cell Lymphoma Unclassified, Intermediate Between Diffuse Large B-Cell Lymphoma And Burkitt Lymphoma: A Single Center Experience Of Intensive Chemotherapy With And Without Auto-Sct

Anna E Lukina,E Baryakh,A M Kovrigina,E G Gemdzhian,V A Misyurin,S K Kravchenko,Vladimir I Vorobyev,Jana K Mangasarova,A U Magomedova, Yuri U Polyakov,T N Obukhova,E Zvonkov,A K Morozova,Valeri G Savchenko

BLOOD（2014）

Cited 23|Views7

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Abstract

Background: According to current data B-cell lymphoma unclassified (BCLU), intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma represents a highly aggressive type of lymphoma with dramatically bad response for chemotherapy. Cases with translocation of two genes (MYC and BCL2 or BCL6) are divided into double-hit lymphomas (DHL). We need to estimate risk factors to intensify treatment and manage indications for autologous stem cell transplantation (auto-SCT) according to individual characteristics.

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Key words

burkitt lymphoma,intensive chemotherapy,b-cell,auto-sct

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