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Evaluation Of Early Glomerulopathy And Tubulopathy In Patients With Transfusion Dependent Thalassemia

BLOOD(2014)

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摘要
Background: We have less information about renal injury in patients with transfusion dependent ß thalassemia (TDT).Cystatin C (Cys-C) is a marker to predict glomerular dysfunction with higher sensitivity and specificity than serum creatinine. Asymptomatic renal tubular dysfunction demonstrated in patients with Beta-thalassaemia who receive deferasirox although age and dose-dependent toxicity profile could not be fully understood.
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关键词
early glomerulopathy,tubulopathy
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