P042: PREVALENCE AND CLINICAL SIGNIFICANCE OF C1q BINDING DONOR SPECIFIC ANTIBODIES IN RENAL TRANSPLANTATION

Adriana Colovai,Christina Savchik,Summeye Calp Inal,Peter Masiakos,Min Ling,Liise K Kayler,Enver Akalin

Human Immunology（2014）

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Abstract

Antibody-mediated injury is a major cause of renal allograft dysfunction and loss. In this study, we aimed to determine the prevalence and clinical significance of complement binding donor-specific antibodies (C1q+DSA) in renal transplant recipients with functioning allografts after 3–30years post-transplantation.

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