Repeated cognitive stimulation alleviates memory impairments in an Alzheimer’s disease mouse model

Stephen T Yeung,Hilda Martinezcoria,Rahasson R Ager,Carlos J Rodriguezortiz,David Bagliettovargas,Frank M Laferla

Brain Research Bulletin（2015）

引用 32|浏览16

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摘要

•Repeated spatial training improves cognitive performance in 3xTg-AD mice.•Repetitive MWM training improves cognition in other hippocampal spatial tasks.•Repetitive MWM training mitigate cognitive deficits in a cortical memory test.

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关键词

Alzheimer’s disease,Hippocampus,Cognitive stimulation,Repeated learning,Morris water maze,3xTg-AD

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