Incidence and Predictors of Cardiac Death in MADIT-II Eligible Korean Patients: Data from KAMIR (Korea Acute Myocardial Infarction Registry)
Journal of Arrhythmia(2011)
Abstract
Introduction: The second Multicenter Automatic Defibrillator Trial (MADIT-II) demonstrated improved survival rate in patients with reduced left ventricular function after myocardial infarction by implantable cardiac defibrillator. We investigated clinical implication of MADIT-II result for Korean population and aimed to identify predictors of cardiac death in MADIT-II eligible patients. Methods: We analyzed 154 patients (male 71.8%, Age 64.7±13.7 yr) from KAMIR (Korea Acute Myocardial Infarction Registry). All enrolled patients were eligible for MADIT II criteria: reduced LV systolic ejection fraction (less than 30%) at 1 month follow up exam after acute myocardial infarction. We checked baseline characteristics, laboratory, echocardiographic and angiographic findings. Clinical outcomes were assessed during 1 year follow up. Results: Demographic data and baseline clinical characteristics were comparable with MADIT-II patients except higher incidence of coronary angioplasty (66.9% in enrolled patients). During follow up period of mean 19.5 months, cardiac death was observed in 12 patients (7.8%) and non cardiac death was developed in 5 patients (3.2%) which were compatible with MADIT-II population. Predictors for cardiac death were advanced age (HR=1.15, p=0.03) and low BMI (HR=3.53, p=0.04). Conclusion: Korean population who were eligible with MADIT-II criteria showed comparable incidence of cardiac death. And low BMI and advanced age were predictors for cardiac death.
MoreTranslated text
Key words
cardiac death,eligible korean patients,myocardial infarction,acute myocardial infarction
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined