Effect of 1,25-dihydroxyvitamin D3 on mast cells tryptase in asthmatic guinea pigs
Asian Pacific Journal of Tropical Medicine（2015）
Abstract
After the asthmatic guinea pigs are treated with 1,25-dihydroxyvitamin D3, their BALF, Re, infiltration degree of inflammatory cells in the trachea and lung tissue and airway inflammatory reaction are reduced significantly. 1,25-dihydroxyvitamin D3 has a certain inhibiting effect on the activation of mast cells and the release of MCT granules.
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Key words
1,25-Dihydroxyvitamin D3,Asthmatic guinea pigs,Expiratory airway resistance,Mast cell tryptase
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