Clinical results of microwave regional coagulation therapy on bladder cancer

Between April 1985 and June 1993, 124 consecutive patients with urinary bladder carcinoma underwent transurethral microwave regional coagulation therapy (MRC). Of these patients, 108 had neither lymphnode metastasis nor distant metastases. We investigated the survival rate and the prognostic significance in the 108 patients. We also performed intracavitary irradiation in patients who had been suffered frequent recurrences. The prognosis of 79 patients with superficial tumor (Ta, Ti, NOMO) and that of 29 patients with muscle infiltrating tumor (T2, T3, NOMO) resulted in the survival rate of 80.7% and 69.0% after 5 years, respectively. The death rate of patients with high grade tumor (G3) was significantly higher than those with G1 and G2 tumors. With MRC the preservation rate of the urinary bladder was 66% in the patients with muscle-infiltrating tumors.In conclusions, these results indicate that we might be able to treat the invasive urinary bladder cancer by MRC without lymphnodes nor distant metastases as well as superficial cancer.