Detection of myocardial metabolic dysfunction caused by the right ventricular apical pacing using thallium 201/iodine 123-labeled beta-methyl iodophenyl pentadecanoic acid SPECT

Ryosuke Higuchi,Nobuo Iguchi,Yuko Utanohara,Kanki Inoue,Jun Umemura,Tetsuya Sumiyoshi,Hitonobu Tomoike

EUROPEAN HEART JOURNAL（2013）

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摘要

Purpose: Many clinical trials have reported that right ventricular apical (RVA) pacing increases the risk of heart failure and atrial fibrillation, but the mechanism remains unknown. Using thallium 201 (Tl)/iodine 123-labeled beta-methyl iodophenyl pentadecanoic acid (BMIPP) single photon emission computed tomography (SPECT), we assessed the hypothesis that RVA pacing has a direct undesirable effect on myocardial metabolism.

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关键词

Cardiovascular Risk Assessment,Cardiac Imaging,Myocardial Perfusion,Cardiac Resynchronization Therapy,Ventricular Arrhythmias

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