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Ligustrazine effect on lipopolysaccharide-induced pulmonary damage in rats

Huiqi Wang,Yuanzhuo Chen,Wenjie Li,Congye Li,Xiangyu Zhang,Hu Peng,Chengjin Gao

Burns（2015）

Cited 13|Views12
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Abstract
•Tetramethylpyrazine (TMP) lessens pulmonary microvascular permeability and alveoli exudation, and relieve lung edema.•In this work, we confirmed the effectiveness of TMP in alleviating acute lung injury (ALI) induced by lipopolysaccharide (LPS).•The CD31+ EMP increase can be regarded as an acute pulmonary vascular endothelial injury behavior.
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Key words
Ligustrazine,LPS,Pulmonary damage,Lung exudative lesion,Vascular endothelial particles
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