Serological monitoring of protection of sheep against Echinococcus granulosus induced by the EG95 vaccine.
Parasite Immunology(2012)
摘要
Although immunity to Echinococcus granulosus in sheep has been shown to be antibody-mediated and complement-dependent and can be passively transferred in colostrum, in animals vaccinated with EG95, the relationship between protection against an oral challenge infection with E. granulosus eggs and anti-EG95 IgG ELISA absorbance values at the time of challenge has not been satisfactorily proven. Using a combination of results from three EG95 vaccination trials, we have found that the IgG ELISA absorbance at the time of challenge infection explains approximately 50% (P <= 0.001) of the variability in the percentage protection against an oral challenge with E. granulosus eggs (transformed with arcsin).
更多查看译文
关键词
cystic echinococcosis,Echinococcus granulosus,EG95 vaccination,hydatid,serology,sheep
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要