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Expression of ferrochelatase has a strong correlation in protoporphyrin IX accumulation with photodynamic detection of bladder cancer

Yasushi Nakai,Yoshihiro Tatsumi,Makito Miyake,Satoshi Anai,Masaomi Kuwada,Sayuri Onishi,Yoshitomo Chihara,Nobumichi Tanaka,Yoshihiko Hirao,Kiyohide Fujimoto

Photodiagnosis and Photodynamic Therapy（2016）

Cited 27|Views9
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Abstract
•We investigated proteins associated with protoporphyrin IX accumulation in bladder cancer cells.•The expression of FECH showed a negative correlation with PPIX accumulation in vitro.•The expression of FECH by IHC was correlated with PPIX accumulation in cancer cells.•The expression of FECH was also correlated with the tumor grade.
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5-Aminolevulinic acid,Protoporphyrin IX,Ferrochelatase
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