P14.07 * DEMOGRAPHICAL AND EPIDEMIOLOGICAL FEATURES OF 5970 ADULT CASES EVALUATED THROUGH THE EGE NEURO-ONCOLOGY BOARD (EGE NORO-ONKOLOJI KONSEYI, ENOK) BETWEEN 1996-2013

Neuro-oncology(2014)

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Abstract
AIM: Since 1996, all of the cases which apply to the Department of Neurological Surgery at Ege University and who undergo a surgery with the pre-diagnosis of a central nervous system tumor, are discussed on the Ege Neuro-oncology Board (Ege Noro-onkoloji Konseyi, ENOK) for further adjuvant treatment and follow-up. Aim of this study is to evaluate the demographical and epidemiological features of the cases enrolled, from 1st January 1996 to 31 December 2013. MATERIAL AND METHODS: Database of Ege Neuro-oncology Board (ENOK) was analyzed retrospectively in this descriptive study. 161 cases younger then 18 years old were excluded. Pathological diagnosis were classified regarding the 2007 world Health Organization (WHO). RESULTS: 5970 adult cases were enrolled and evaluated on the board of ENOK, between 1996 and 2013. It is detected that until 2005, number of cases enrolled were less then 300 per year and exceeded 400 per year after 2006. 484 (8.1%) of the all cases were non-tumoral. 49 (0.8%) cases were not operated due to lack of consent or other medical conditions. Total number of the all cases who were performed a surgery was 5437. 50.7% was male. The most common age group of the patients was 50-59 with 1289 cases (23.7%). The second most common age group was 40-49 consisting 1154 (21.2%) cases. The origin of the tumors was classified as neuro-epithelial tissue in 1586 (29.2%), meninges in 1319 (24.3%), pituitary in 736 (13.5%), metastasis in 650 (12.0%), cranial and peripheral nerves in 389 (7.2%), others in 262 (4.8%), un-certain in 211 (3.9%), lymphoma and other hem poetic in 124 (2.1%), sellar region in 74 (1.4%), mixt in 38 (0.7%), germ cell in 16 (0.3%) of the cases. The most common tumors diagnosed with female had meningeal origins (n = 906, 33.9%). The most common tumors diagnosed with male were neuro-epithelial tumors (n = 940, 34.1%). The second most common for female were neuro-epithelial tumors (n = 645, 24.1%) as for male were metastasis (n = 447, 16.2%). DISCUSSION AND CONCLUSION: Multi-disciplinary tumor boards in neuro-oncology are essential for treatment planning of each individual case. They also supply unique databases for epidemiological and demographical surveys. Especially in the developing world official medical registries may lack of certain and sufficient scientific data and detail. High volume neuro-oncological databases may be constituted only when the boards assembly regularly and keep its recordings meticulously for long period of years. Our epidemiological results are in parallel with the existing literature.
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Key words
epidemiological features,adult cases,neuro-oncology,noro-onkoloji
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